Kawasaki’s disease (Mucocutaneous lymph node syndrome)

a multisystemic necrotizing medium vessel vasculitis

largely seen in children under 5 years of age

etiology:

autoimmune disease

pre-existing viral infection trigger

Manifestatations:

multi-organ affects

  • erythmatous peidermis
  • erythmatous muscous membranes
  • cervial lymph node enlargement
  • blood vessel walls
  • heart – can cause severe aneurysmal dilations in untreated children
  • edema in hands and feet
  • fever may accompany other symptoms

Treatment:

  • corticosteriods
  • Immunogolgulin therapy
  • NSAIDs – asprin

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