Mechanism of Diabetic Angiopathy

  1. high blood sugar levels are present
  2. results in the formation of glycated end products
  3. these metabolic waste products stick to the blood vessel walls
  4. immune complexes adhere to them
  5. inflammation occurs
  6. platelets adhere to the complex
  7. atherosclerosis (lipids adhere to vessel walls)
  8. results in hypertension
  9. ischemia
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