D-dimer assay is a diagnostic test used to rule-out deep venous thrombosis (DVT). The D-dimer is a degraded fibrin protein that is present in the blood after a thrombus (blood clot) has been degraded by fibrinolysis. The D-dimer concentration may be determined by a blood assay in conjunction with other diagnostics tests such as ultrasound and angiogram to diagnose thrombosis.
Deep vein thrombosis assessment, diagnostics and treatment
Martin, Glenn and Porth, Carol, Mattson. 2009. Pathophysiology Concepts of Altered Health States. 8th ed. Lippincott Williams and Wilkins. Philadelphia