Burkitt lymphoma (Malignant lymphoma, Burkitt’s type)

A type of non-Hodgkin’s lymphoma. a cancer of the lymphatic system. a type of cancer found in the T and B cells of the immune system. most frequently occurs in the abdomen, the ovaries, and the bones of the face.

Etiology:

It is associated with malaria

It accounts for about 30% of HIV-associated lymphomas.

Chromosomal translocations have been associated with this type of cancer. In most (approximately 90%) of the cases of Burkitt’s lymphoma, a reciprocal translocation has moved the proto-oncogene c-myc from its normal position on chromosome 8 to a location close to the enhancers of the antibody heavy chain genes on chromosome 14.

 

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