Global Development Delay

Delayed achievement of a number of key developmental milestones eg. Conditions such as Down’s Syndrome, Rett’s Syndrome and Fragile X Syndrome.

Common signs may include:

  • delayed acquisition of milestones: the child is late in sitting up, crawling, walking
  • limited reasoning or conceptual abilities
  • fine/gross motor difficulties
  • poor social skills/judgment
  • aggressive behaviour as a coping skill
  • communication problems

The following lists complicating factors that may cause symptoms of developmental delays.

 Differential diagnosis of global developmental delay• Infection (congenital)

• Trauma

• Exposure to toxins

• Uncontrolled seizures

• Asphyxia or hypoxic ischemic


• Structural brain abnormality

• Genetic, syndromic or

neurocutaneous disorder

• Inborn error of metabolism

• Endocrinopathy

• Severe environmental deprivation

or neglect

• Malnutrition or failure to thrive




The Sound Learning Center. 2009. Glossary. Retrieved August 15, 2009 from

2006. Teaching Case Report. A child with an underecognized form of global developmental disorder: a congenital disorder of glycosylation. Practice. 175 (11) 1369-1370.


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